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      goedmedicine
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      <p style=”box-sizing: border-box; padding: 0px; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; color: #000000; margin: 0px 0px var(–wd-tags-mb) 0px;”><span style=”font-weight: 700 !important;”>Fildena 100mg Tablet</span> contains the active ingredient Sildenafil , which belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Here’s how it works:</p>
      <p style=”box-sizing: border-box; padding: 0px; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; color: #000000; margin: 0px 0px var(–wd-tags-mb) 0px;”><span style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: 600; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>1. Erection Physiology:</span></p>

      <ul style=”box-sizing: border-box; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; list-style-position: initial; list-style-image: initial; –list-mb: 20px; –li-mb: 10px; –li-pl: 17px; color: #000000; padding: 0px 0px 0px var(–li-pl); margin: 0px 0px var(–list-mb) 0px;”>
      <li style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>To understand how <span style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>Fildena </span>works, it’s important to know the basics of how an erection occurs. When a man is sexually aroused, nitric oxide is released in the <span style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>erectile </span>tissue of the penis. This nitric oxide triggers an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP).

      <p style=”box-sizing: border-box; padding: 0px; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; color: #000000; margin: 0px 0px var(–wd-tags-mb) 0px;”><span style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: 600; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>2. Role of cGMP:</span></p>

      <ul style=”box-sizing: border-box; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; list-style-position: initial; list-style-image: initial; –list-mb: 20px; –li-mb: 10px; –li-pl: 17px; color: #000000; padding: 0px 0px 0px var(–li-pl); margin: 0px 0px var(–list-mb) 0px;”>
      <li style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>cGMP is a signaling molecule that relaxes and dilates the blood vessels in the penis. This allows blood to flow into the erectile tissues, causing an erection.

      <p style=”box-sizing: border-box; padding: 0px; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; color: #000000; margin: 0px 0px var(–wd-tags-mb) 0px;”><span style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: 600; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>3. PDE5 Enzyme:</span></p>

      <ul style=”box-sizing: border-box; border: 0px; vertical-align: baseline; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-stretch: inherit; line-height: inherit; font-family: Inter, Arial, Helvetica, sans-serif; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-size: 14px; list-style-position: initial; list-style-image: initial; –list-mb: 20px; –li-mb: 10px; –li-pl: 17px; color: #000000; padding: 0px 0px 0px var(–li-pl); margin: 0px 0px var(–list-mb) 0px;”>
      <li style=”box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; vertical-align: baseline; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit;”>However, an enzyme called phosphodiesterase type 5 (PDE5) naturally breaks down cGMP. This can lead to a reduction in blood flow to the penis, making it difficult to achieve or maintain an erection.

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